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Year : 2019  |  Volume : 3  |  Issue : 1  |  Page : 54

Osteoclastoma at the maxillofacial region

Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Web Publication22-Aug-2019

Correspondence Address:
Prof. Mahmood Dhahir Al-Mendalawi
P. O. Box: 55302, Baghdad Post Office, Baghdad
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/aiao.aiao_30_18

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How to cite this article:
Al-Mendalawi MD. Osteoclastoma at the maxillofacial region. Ann Indian Acad Otorhinolaryngol Head Neck Surg 2019;3:54

How to cite this URL:
Al-Mendalawi MD. Osteoclastoma at the maxillofacial region. Ann Indian Acad Otorhinolaryngol Head Neck Surg [serial online] 2019 [cited 2020 May 29];3:54. Available from: http://www.aiaohns.in/text.asp?2019/3/1/54/265136


I read with great interest the case report by Swain et al.[1] published in the January–June 2018 issue of the Annals of Indian Academy of Otorhinolaryngology Head and Neck Surgery. It is obvious that osteoclastoma or giant cell tumor is a rare neoplasm of the bone that often affects long bones. The authors described nicely the clinical picture and the histopathological and imaging findings as well as the surgical intervention of the osteoclastoma at the maxillofacial region in an Indian patient.[1] I presume that that rare occurrence of that neoplasm at an unusual site should alert the authors to consider impaired immune status in the index case. Among conditions associated with impaired immunity, infection with human immunodeficiency virus (HIV) is paramount. My presumption is based on the following point. It is explicit that due to the low immunity, coinfection with oncogenic viruses, and life prolongation secondary to the use of antiretroviral therapy, patients infected with HIV are more vulnerable to various types of neoplasms compared to individuals with healthy immune system.[2] Among these neoplasms, osteoclastoma has been reported in HIV-positive patients.[3] India is one of the Asian countries confronting the grave health consequences of HIV infection. Although no recent data are yet present on the exact HIV seroprevalence in India, the available data pointed out to 0.26% seroprevalence compared with a global average of 0.2%.[4] I presume that contemplating the diagnostic set of blood CD4 lymphocyte count and viral overload measurements was envisaged in the studied patient. If that set was to show HIV positivity, the case in question could be really regarded as a novel case report of HIV-associated maxillofacial osteoclastoma in India.

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  References Top

Swain SK, Bhattacharyya B, Sahu MC. Osteoclastoma at the maxillofacial region. Ann Indian Acad Otorhinolaryngol Head Neck Surg 2018;2:12-4.  Back to cited text no. 1
  [Full text]  
Valencia Ortega ME. Malignancies and infection due to the human immunodeficiency virus. Are these emerging diseases? Rev Clin Esp 2018;218:149-55.  Back to cited text no. 2
Ares O, Conesa X, Seijas R, Huguet P, González R, Fernández N, et al. Giant cell tumor of bone in a patient with HIV infection. Enferm Infecc Microbiol Clin 2010;28:396-7.  Back to cited text no. 3
Paranjape RS, Challacombe SJ. HIV/AIDS in India: An overview of the Indian epidemic. Oral Dis 2016;22 Suppl 1:10-4.  Back to cited text no. 4


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