• Users Online: 166
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
REVIEW ARTICLE
Year : 2019  |  Volume : 3  |  Issue : 1  |  Page : 1-7

Current status of cell-free DNA in head and neck cancer management


Department of Surgical Oncology, RMLIMS, Lucknow, Uttar Pradesh, India

Correspondence Address:
Dr. Akhlak Hussain
Department of Surgical Oncology, RMLIMS, Lucknow, Uttar Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aiao.aiao_32_18

Get Permissions

Tissue biopsies are temporally and spatially limited and often provide a brief snapshot of a single region of a heterogeneous tumor. Carcinogenesis is a complex process in which heterogeneity plays an important role in the development and progression. Research efforts are going on focusing on the discovery of new, noninvasive methods for the diagnosis, and comprehension of the tumor genomic architecture to monitor tumor evolution and therapeutic response in real time. Liquid biopsy is a noninvasive diagnostic tool that can provide a personalized snapshot of primary and metastatic tumor at successive time points, providing knowledge of the tumor burden so as to detect early evidence of recurrence or resistance to the disease and helping clinicians in their therapeutic decision-making. Therefore, using liquid biopsies, we can obtain a molecular profile for each patient. We intended to review cell-free DNA (cfDNA) in oral cancer. We described cfDNA considering their levels, diagnostic value, prognostic value, predictive value.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed277    
    Printed26    
    Emailed0    
    PDF Downloaded55    
    Comments [Add]    

Recommend this journal